• Numerous clinical trials phase II and phase

  2019-06-11

  

  Numerous clinical trials (phase II and phase III) have been then designed to evaluate the efficacy of denosumab in oncology mainly in breast and prostate bone metastases (Table 1). These studies revealed that denosumab reduced significantly bone turnover markers similarly to osteoporotic patients. M

• Most infants in NICUs are hospitalized

  2019-06-10

  

  Most infants in NICUs are hospitalized continuously from birth, and MRSA infections are largely considered to be horizontally transmitted. Various studies had reported that viable MRSA can be found on the hands of up to 17% of healthcare workers, and on 59% of the environmental surfaces in rooms of

• Ja s et al reported

  2019-06-10

  

  Jaïs et al. reported that complete LAVA elimination is a better predictor of success than the absence of inducibility [23]. Achieving complete elimination of LAVA yields superior survival free from recurrent VT during long-term follow-up. Scar homogenization significantly increases the freedom from

• Approximately of the patients who developed BM during their

  2019-06-10

  

  Approximately 50% of the patients who developed BM during their palliative disease course received BM-related radiotherapy and/or surgery; 12% of the patients received both therapy options. Our data confirms that the majority of patients with BM will respond to a low course of radiotherapy with good

• Digoxigenin-11-dUTP Los antecedentes que en este sentido se

  2019-06-10

  

  Los antecedentes que en este sentido se agradecen son las referencias a los géneros —forense y epidíptico— que convergen en los discursos de quienes presenciaron los acontecimientos de la Conquista. Herencias del medioevo: la tradición bíblica, fábulas y el imaginario pagano, detrás de los que exist

• Cholangiopathies are a group of rare diseases whose primary

  2019-06-10

  

  Cholangiopathies are a group of rare diseases whose primary or secondary target is the cholangiocyte. The onset and subsequent development processes of cholangiopathies are extremely diverse, with causes that are genetic, neoplastic, immune-mediated, idiopathic, infectious, and toxin- or drug-induce

• Pregnancies in adolescents year olds and

  2019-06-10

  

  Pregnancies in adolescents (10–19-year-olds) and in older women (≥35 years) are hazardous for the mother and the child. Despite an almost universal decline in the adolescent adrenergic receptors since 1990, adolescent fertility still accounts for 11% of all births worldwide, with 95% of these births

• thyroid hormone receptor br Consideracj es fin is De acordo

  2019-06-10

  

  Consideracjóes fináis De acordo com as evidências coletadas com thyroid hormone receptor pesquisa, algumas discussões passam a ser sugeridas. Inicialmente, das parcerias entre Estado e sociedade foram abertas vagas na saúde públicas a serem ocupadas por “pessoas jurídicas de direito privados”, e

• In this study we analyzed the

  2019-06-10

  

  In this study, we analyzed the biological effects of two novel GATA2 mutations, which were identified in adult de novo AML patients. Materials and methods The diagnosis of AML was based on the morphology, histopathology, the expression of leukocyte differentiation 7 8-dihydroxyflavone and/or th

• br As the global burden

  2019-06-10

  

  As the global burden of disease shifts from infectious diseases to non-communicable diseases (NCDs), cancer has increasingly become a major contributor to morbidity and mortality in low-income and middle-income countries (LMICs). Major reasons for these purchase (±)-Nutlin-3 shifts include increa

• mg115 br Genetic basis Similar to other arrhythmia syndromes

  2019-06-10

  

  Genetic basis Similar to other arrhythmia syndromes, Brugada and early repolarization syndromes are inherited diseases that are usually transmitted in an autosomal-dominant manner [26]. To date, 13 genes have been associated with Brugada syndrome. Loss-of-function mutations in SCN5A, encoding the

• br Case report A year old man with dilated

  2019-06-10

  

  Case report A 68-year-old man with dilated cardiomyopathy [Left ventricular (LV) ejection fraction, 15%] of unknown etiology and nonsustained ventricular tachycardia was referred to our institution. He was prescribed a β-blocker (2.5mg of carvedilol, which was gradually increased to 20mg) and 200

• A number of studies have shown

  2019-06-10

  

  A number of studies have shown that zoledronic glycine receptors has the ability to potentiate effects of anti-tumor agents such as doxorubicin [21] or everolimus [22]. In a recent paper the combination of chemotherapy with a single infusion of 4mg zoledronic acid in patients with breast cancer was

• Treatment options for elderly AML must be based on

  2019-06-06

  

  Treatment options for elderly AML must be based on four main factors: patient\'s clinical condition, disease characteristics, patient wishes and social support. Thus, the most frail and oldest among the oldest will have the least net benefit from chemotherapy or hematopoietic transplantation, even i

• India is the second largest consumer and third largest produ

  2019-06-06

  

  India is the second largest consumer and third largest producer of tobacco in the world. The Indian Government has been significantly engaged in addressing the tobacco problem. A major policy, the Cigarettes and Other Tobacco Products Act (COTPA) was implemented in 2003, followed by WHO\'s Framework

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